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M94A2908.TXT
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1994-10-25
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Document 2908
DOCN M94A2908
TI Risk factors for retinal detachment in patients with CMV-retinitis.
DT 9412
AU Geier SA; Sadri I; Bogner JR; Klauss V; Goebel FD; Medizinische
Poliklinik LMU, Munich, FRG.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):197 (abstract no. PB0218). Unique
Identifier : AIDSLINE ICA10/94369667
AB OBJECTIVE: The purpose of this study was to investigate risk factors
associated with retinal detachment in patients with AIDS and
CMV-retinitis. PATIENTS AND METHODS: 69 patients with CMV-retinits were
evaluated with respect to peripheral involvement of the retina. Myopia
was evaluated as an additional not CMV-retinitis-related risk factor.
RESULTS: Retinal detachment occurred in 12 patients (17%). In all 12
patients (100%) with retinal detachment peripheral involvement (zone 3)
was observed compared with 23 patients (40%) without retinal detachment.
This accounts for a relative risk (RR) of 2.5 (p < 0.001). Myopia was
observed in 10 patients (83%) with retinal detachment, and in 9 patients
(16%) without retinal detachment. This accounts for a RR of 5.2 (p <
0.001). A multivariate analysis demonstrated that zone 3 involvement
remained a significant risk factor when controlling for myopia.
CONCLUSION: Peripheral involvement and myopia are independent risk
factors for the occurrence of retinal detachment. As
pars-plana-vitrectomy with silicone-oil tamponade is successful in
patients with AIDS a close monitoring is necessary in patients at risk
for development of retinal detachment.
DE AIDS-Related Opportunistic Infections/*COMPLICATIONS Cytomegalovirus
Infections/COMPLICATIONS Cytomegalovirus Retinitis/*COMPLICATIONS
Human Myopia/*COMPLICATIONS Retinal Detachment/EPIDEMIOLOGY/*ETIOLOGY
Risk Factors Support, Non-U.S. Gov't MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).